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Pharmacokinetics and Dosing Regimens of Direct Oral Anticoagulants in Morbidly Obese Patients: An Updated Literature Review

Data on the impact of morbid obesity (body mass index [BMI] ≥ 40 kg/m(2)) on the pharmacokinetics (PK), pharmacodynamics (PD) of direct oral anticoagulants (DOACs) are relatively limited, making it difficult to design optimal dosing regimens in morbidly obese patients. To review literature on PK/PD...

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Detalles Bibliográficos
Autores principales: Zhao, Ying, Guo, Mingxing, Li, Dandan, Xu, Wanyi, Pan, Chen, He, Chaoran, Cui, Xiangli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943962/
https://www.ncbi.nlm.nih.gov/pubmed/36760080
http://dx.doi.org/10.1177/10760296231153638