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Pharmacokinetics and Dosing Regimens of Direct Oral Anticoagulants in Morbidly Obese Patients: An Updated Literature Review
Data on the impact of morbid obesity (body mass index [BMI] ≥ 40 kg/m(2)) on the pharmacokinetics (PK), pharmacodynamics (PD) of direct oral anticoagulants (DOACs) are relatively limited, making it difficult to design optimal dosing regimens in morbidly obese patients. To review literature on PK/PD...
Autores principales: | Zhao, Ying, Guo, Mingxing, Li, Dandan, Xu, Wanyi, Pan, Chen, He, Chaoran, Cui, Xiangli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943962/ https://www.ncbi.nlm.nih.gov/pubmed/36760080 http://dx.doi.org/10.1177/10760296231153638 |
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