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The IDI1/SREBP2 axis drives intrahepatic cholestasis and is a treatment target of San-Huang-Cai-Zhu formula identified by sequencing and experiments

San-Huang-Chai-Zhu formula (SHCZF), originates from Da-Huang-Xiao-Shi decoction (DHXSD) for the treatment of jaundice as recorded in the Chinese traditional Chinese medicine book Jin Gui Yao Lue. In the clinic, SHCZF has been used to treat cholestasis-related liver disease by improving intrahepatic...

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Detalles Bibliográficos
Autores principales: Yan, Junbin, Nie, Yunmeng, Chen, Zheng, Yao, Jiaming, Zhang, Shuo, Chen, Zhiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944032/
https://www.ncbi.nlm.nih.gov/pubmed/36843951
http://dx.doi.org/10.3389/fphar.2023.1093934