Bioprocess Development and Characterization of a (13)C-Labeled Hybrid Bispecific Antibody Produced in Escherichia coli

Monoclonal antibodies (mAbs) are highly efficacious therapeutics; however, due to their large, dynamic nature, structural perturbations and regional modifications are often difficult to study. Moreover, the homodimeric, symmetrical nature of mAbs makes it difficult to elucidate which heavy chain (HC...

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Detalles Bibliográficos
Autores principales: Wecksler, Aaron T., Lundin, Victor, Williams, Ambrose J., Veeravalli, Karthik, Reilly, Dorothea E., Grieco, Sung-Hye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944054/
https://www.ncbi.nlm.nih.gov/pubmed/36810521
http://dx.doi.org/10.3390/antib12010016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944054/
https://www.ncbi.nlm.nih.gov/pubmed/36810521
http://dx.doi.org/10.3390/antib12010016

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