Cargando…
Bioprocess Development and Characterization of a (13)C-Labeled Hybrid Bispecific Antibody Produced in Escherichia coli
Monoclonal antibodies (mAbs) are highly efficacious therapeutics; however, due to their large, dynamic nature, structural perturbations and regional modifications are often difficult to study. Moreover, the homodimeric, symmetrical nature of mAbs makes it difficult to elucidate which heavy chain (HC...
Autores principales: | Wecksler, Aaron T., Lundin, Victor, Williams, Ambrose J., Veeravalli, Karthik, Reilly, Dorothea E., Grieco, Sung-Hye |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944054/ https://www.ncbi.nlm.nih.gov/pubmed/36810521 http://dx.doi.org/10.3390/antib12010016 |
Ejemplares similares
-
Epitope mapping of anti-drug antibodies to a clinical candidate bispecific antibody
por: Schick, Arthur J., et al.
Publicado: (2022) -
Strain engineering and bioprocessing strategies for biobased production of porphobilinogen in Escherichia coli
por: Lall, Davinder, et al.
Publicado: (2021) -
Enzymatic basis of the Fc-selective intra-chain disulfide reduction and free thiol content variability in an antibody produced in Escherichia coli
por: Baginski, Tomasz K., et al.
Publicado: (2022) -
Engineering Escherichia coli for succinate production from hemicellulose via consolidated bioprocessing
por: Zheng, Zongbao, et al.
Publicado: (2012) -
Development and characterization of Escherichia coli triple reporter strains for investigation of population heterogeneity in bioprocesses
por: Heins, Anna-Lena, et al.
Publicado: (2020)