Characterization of an IDH1 R132H Rabbit Monoclonal Antibody, MRQ-67, and Its Applications in the Identification of Diffuse Gliomas

The current diagnosis of diffuse glioma involves isocitrate dehydrogenase (IDH) mutation testing. Most IDH mutant gliomas carry a G-to-A mutation at IDH1 position 395, resulting in the R132H mutant. R132H immunohistochemistry (IHC), therefore, is used to screen for the IDH1 mutation. In this study,...

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Detalles Bibliográficos
Autores principales: Copaciu, Raul, Rashidian, Juliet, Lloyd, Joshua, Yahyabeik, Aril, McClure, Jennifer, Cummings, Kelsea, Su, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944093/
https://www.ncbi.nlm.nih.gov/pubmed/36810519
http://dx.doi.org/10.3390/antib12010014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944093/
https://www.ncbi.nlm.nih.gov/pubmed/36810519
http://dx.doi.org/10.3390/antib12010014

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