Characterization of Active MMP9 in Chronic Inflammatory Diseases Using a Novel Anti-MMP9 Antibody

Matrix metalloproteinase 9 (MMP9), a protease implicated in multiple diseases, is secreted as an inactive zymogen and requires proteolytic removal of the pro-domain for activation. The relative levels and functionality of the pro- and active-MMP9 isoforms in tissues are not characterized. We generat...

Descripción completa

Detalles Bibliográficos
Autores principales: Velasquez, Maile, O’Sullivan, Chris, Brockett, Robert, Mikels-Vigdal, Amanda, Mikaelian, Igor, Smith, Victoria, Greenstein, Andrew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944116/
https://www.ncbi.nlm.nih.gov/pubmed/36810514
http://dx.doi.org/10.3390/antib12010009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944116/
https://www.ncbi.nlm.nih.gov/pubmed/36810514
http://dx.doi.org/10.3390/antib12010009

Ejemplares similares