Beyond a platform protein for the degradosome assembly: The Apoptosis-Inducing Factor as an efficient nuclease involved in chromatinolysis

The Apoptosis-Inducing Factor (AIF) is a moonlighting flavoenzyme involved in the assembly of mitochondrial respiratory complexes in healthy cells, but also able to trigger DNA cleavage and parthanatos. Upon apoptotic-stimuli, AIF redistributes from the mitochondria to the nucleus, where upon associ...

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Detalles Bibliográficos
Autores principales: Novo, Nerea, Romero-Tamayo, Silvia, Marcuello, Carlos, Boneta, Sergio, Blasco-Machin, Irene, Velázquez-Campoy, Adrián, Villanueva, Raquel, Moreno-Loshuertos, Raquel, Lostao, Anabel, Medina, Milagros, Ferreira, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944232/
https://www.ncbi.nlm.nih.gov/pubmed/36845352
http://dx.doi.org/10.1093/pnasnexus/pgac312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944232/
https://www.ncbi.nlm.nih.gov/pubmed/36845352
http://dx.doi.org/10.1093/pnasnexus/pgac312

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