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Time-restricted feeding promotes muscle function through purine cycle and AMPK signaling in Drosophila obesity models

Obesity caused by genetic and environmental factors can lead to compromised skeletal muscle function. Time-restricted feeding (TRF) has been shown to prevent muscle function decline from obesogenic challenges; however, its mechanism remains unclear. Here we demonstrate that TRF upregulates genes inv...

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Detalles Bibliográficos
Autores principales: Livelo, Christopher, Guo, Yiming, Abou Daya, Farah, Rajasekaran, Vasanthi, Varshney, Shweta, Le, Hiep D., Barnes, Stephen, Panda, Satchidananda, Melkani, Girish C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944249/
https://www.ncbi.nlm.nih.gov/pubmed/36810287
http://dx.doi.org/10.1038/s41467-023-36474-4