A novel transgenic mouse model expressing primate-specific nuclear choline acetyltransferase: insights into potential cholinergic vulnerability

The acetylcholine (ACh) synthesizing enzyme choline acetyltransferase (ChAT) is an important cholinergic neuronal marker whose levels and/or activity are reduced in physiological and pathological aging. One isoform of ChAT, 82-kDa ChAT, is expressed only in primates and found primarily in nuclei of...

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Detalles Bibliográficos
Autores principales: AlQot, H. E., Rylett, R. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944276/
https://www.ncbi.nlm.nih.gov/pubmed/36810877
http://dx.doi.org/10.1038/s41598-023-30155-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944276/
https://www.ncbi.nlm.nih.gov/pubmed/36810877
http://dx.doi.org/10.1038/s41598-023-30155-4

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