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IGF-1 boosts mitochondrial function by a Ca(2+) uptake-dependent mechanism in cultured human and rat cardiomyocytes

A physiological increase in cardiac workload results in adaptive cardiac remodeling, characterized by increased oxidative metabolism and improvements in cardiac performance. Insulin-like growth factor-1 (IGF-1) has been identified as a critical regulator of physiological cardiac growth, but its prec...

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Detalles Bibliográficos
Autores principales: Sánchez-Aguilera, Pablo, López-Crisosto, Camila, Norambuena-Soto, Ignacio, Penannen, Christian, Zhu, Jumo, Bomer, Nils, Hoes, Matijn F., Van Der Meer, Peter, Chiong, Mario, Westenbrink, B. Daan, Lavandero, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944404/
https://www.ncbi.nlm.nih.gov/pubmed/36846332
http://dx.doi.org/10.3389/fphys.2023.1106662