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Noncanonical amino acids as doubly bio-orthogonal handles for one-pot preparation of protein multiconjugates
Genetic encoding of noncanonical amino acid (ncAA) for site-specific protein modification has been widely applied for many biological and therapeutic applications. To efficiently prepare homogeneous protein multiconjugates, we design two encodable noncanonical amino acids (ncAAs), 4-(6-(3-azidopropy...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944564/ https://www.ncbi.nlm.nih.gov/pubmed/36810592 http://dx.doi.org/10.1038/s41467-023-36658-y |