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Fecal microbiome transplantation and tributyrin improves early cardiac dysfunction and modifies the BCAA metabolic pathway in a diet induced pre-HFpEF mouse model

More than 50% of patients with heart failure present with heart failure with preserved ejection fraction (HFpEF), and 80% of them are overweight or obese. In this study we developed an obesity associated pre-HFpEF mouse model and showed an improvement in both systolic and diastolic early dysfunction...

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Detalles Bibliográficos
Autores principales: Hatahet, Jomana, Cook, Tyler M., Bonomo, Raiza R., Elshareif, Nadia, Gavini, Chaitanya K., White, Chelsea R., Jesse, Jason, Mansuy-Aubert, Virginie, Aubert, Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944585/
https://www.ncbi.nlm.nih.gov/pubmed/36844730
http://dx.doi.org/10.3389/fcvm.2023.1105581