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Fecal microbiome transplantation and tributyrin improves early cardiac dysfunction and modifies the BCAA metabolic pathway in a diet induced pre-HFpEF mouse model
More than 50% of patients with heart failure present with heart failure with preserved ejection fraction (HFpEF), and 80% of them are overweight or obese. In this study we developed an obesity associated pre-HFpEF mouse model and showed an improvement in both systolic and diastolic early dysfunction...
Autores principales: | Hatahet, Jomana, Cook, Tyler M., Bonomo, Raiza R., Elshareif, Nadia, Gavini, Chaitanya K., White, Chelsea R., Jesse, Jason, Mansuy-Aubert, Virginie, Aubert, Gregory |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944585/ https://www.ncbi.nlm.nih.gov/pubmed/36844730 http://dx.doi.org/10.3389/fcvm.2023.1105581 |
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