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Autocrine TNF-α Increases Penetration of Myelin-Associated Glycoprotein Antibodies Across the Blood-Nerve Barrier in Anti-MAG Neuropathy

BACKGROUND AND OBJECTIVES: Deposition of myelin-associated glycoprotein (MAG) immunoglobulin M (IgM) antibodies in the sural nerve is a key feature in anti-MAG neuropathy. Whether the blood-nerve barrier (BNB) is disrupted in anti-MAG neuropathy remains elusive.We aimed to evaluate the effect of ser...

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Detalles Bibliográficos
Autores principales: Sato, Ryota, Shimizu, Fumitaka, Kuwahara, Motoi, Mizukami, Yoichi, Watanabe, Kenji, Maeda, Toshihiko, Sano, Yasuteru, Takeshita, Yukio, Koga, Michiaki, Kusunoki, Susumu, Kanda, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944621/
https://www.ncbi.nlm.nih.gov/pubmed/36810162
http://dx.doi.org/10.1212/NXI.0000000000200086