Inhibition of myeloperoxidase enhances immune checkpoint therapy for melanoma

BACKGROUND: The presence of a highly immunosuppressive tumor microenvironment has limited the success of immune checkpoint therapy (ICT). Immune suppressing myeloid cells with increased production of reactive oxygen species are critical drivers of this immunosuppressive tumor microenvironment. Strat...

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Detalles Bibliográficos
Autores principales: Liu, Tracy W, Gammon, Seth T, Yang, Ping, Ma, Wencai, Wang, Jing, Piwnica-Worms, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944647/
https://www.ncbi.nlm.nih.gov/pubmed/36805920
http://dx.doi.org/10.1136/jitc-2022-005837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944647/
https://www.ncbi.nlm.nih.gov/pubmed/36805920
http://dx.doi.org/10.1136/jitc-2022-005837

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