Cargando…

Two birds one stone: β-fluoropyrrolyl-cysteine S(N)Ar chemistry enabling functional porphyrin bioconjugation

Bioconjugation, a synthetic tool that endows small molecules with biocompatibility and target specificity through covalent attachment of a biomolecule, holds promise for next-generation diagnosis or therapy. Besides the establishment of chemical bonding, such chemical modification concurrently allow...

Descripción completa

Detalles Bibliográficos
Autores principales: Jin, Guo-Qing, Wang, Jing-Xiang, Lu, Jianhua, Zhang, Hang, Yao, Yuhang, Ning, Yingying, Lu, Hua, Gao, Song, Zhang, Jun-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944650/
https://www.ncbi.nlm.nih.gov/pubmed/36845938
http://dx.doi.org/10.1039/d2sc06209g