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Cell Immortalization: In Vivo Molecular Bases and In Vitro Techniques for Obtention

Somatic human cells can divide a finite number of times, a phenomenon known as the Hayflick limit. It is based on the progressive erosion of the telomeric ends each time the cell completes a replicative cycle. Given this problem, researchers need cell lines that do not enter the senescence phase aft...

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Detalles Bibliográficos
Autores principales: de Bardet, Javier Curi, Cardentey, Celeste Ramírez, González, Belkis López, Patrone, Deanira, Mulet, Idania Lores, Siniscalco, Dario, Robinson-Agramonte, María de los Angeles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944833/
https://www.ncbi.nlm.nih.gov/pubmed/36810441
http://dx.doi.org/10.3390/biotech12010014