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Structural insights into substrate recognition and translocation of human peroxisomal ABC transporter ALDP

Dysfunctions of ATP-binding cassette, subfamily D, member 1 (ABCD1) cause X-linked adrenoleukodystrophy, a rare neurodegenerative disease that affects all human tissues. Residing in the peroxisome membrane, ABCD1 plays a role in the translocation of very long-chain fatty acids for their β-oxidation....

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Detalles Bibliográficos
Autores principales: Xiong, Chao, Jia, Li-Na, Xiong, Wei-Xi, Wu, Xin-Tong, Xiong, Liu-Lin, Wang, Ting-Hua, Zhou, Dong, Hong, Zhen, Liu, Zheng, Tang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944889/
https://www.ncbi.nlm.nih.gov/pubmed/36810450
http://dx.doi.org/10.1038/s41392-022-01280-9