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The impact of hypoxia and oxidative stress on proteo-metabolomic alterations of 3D cholangiocarcinoma models
The three-dimensional multicellular spheroid (3D MCS) model has been employed in cholangiocarcinoma research as it generates 3D architecture and includes more physiological relevance with the multicellular arrangement. However, it is also essential to explain the molecular signature in this microenv...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944917/ https://www.ncbi.nlm.nih.gov/pubmed/36810897 http://dx.doi.org/10.1038/s41598-023-30204-y |