Cargando…
The impact of hypoxia and oxidative stress on proteo-metabolomic alterations of 3D cholangiocarcinoma models
The three-dimensional multicellular spheroid (3D MCS) model has been employed in cholangiocarcinoma research as it generates 3D architecture and includes more physiological relevance with the multicellular arrangement. However, it is also essential to explain the molecular signature in this microenv...
Autores principales: | Phukhum, Pimpawadee, Phetcharaburanin, Jutarop, Chaleekarn, Kwuanjira, Kittirat, Yingpinyapat, Kulthawatsiri, Thanaporn, Namwat, Nisana, Loilome, Watcharin, Khuntikeo, Narong, Titapun, Attapol, Wangwiwatsin, Arporn, Khampitak, Tueanjit, Suksawat, Manida, Klanrit, Poramate |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944917/ https://www.ncbi.nlm.nih.gov/pubmed/36810897 http://dx.doi.org/10.1038/s41598-023-30204-y |
Ejemplares similares
-
Metabolomic analyses uncover an inhibitory effect of niclosamide on mitochondrial membrane potential in cholangiocarcinoma cells
por: Kulthawatsiri, Thanaporn, et al.
Publicado: (2023) -
Interleukin-6-derived cancer-associated fibroblasts activate STAT3 pathway contributing to gemcitabine resistance in cholangiocarcinoma
por: Kittirat, Yingpinyapat, et al.
Publicado: (2022) -
CD44 modulates metabolic pathways and altered ROS-mediated Akt signal promoting cholangiocarcinoma progression
por: Thanee, Malinee, et al.
Publicado: (2021) -
Chemotherapeutic resistant cholangiocarcinoma displayed distinct intratumoral microbial composition and metabolic profiles
por: Sitthirak, Sirinya, et al.
Publicado: (2022) -
(1)H NMR fecal metabolic phenotyping of periductal fibrosis- and cholangiocarcinoma-specific metabotypes defining perturbation in gut microbial-host co-metabolism
por: Treeriya, Rujikorn, et al.
Publicado: (2023)