Mutation in Smek2 regulating hepatic glucose metabolism causes hypersarcosinemia and hyperhomocysteinemia in rats

Suppressor of mek1 (Dictyostelium) homolog 2 (Smek2), was identified as one of the responsible genes for diet-induced hypercholesterolemia (DIHC) of exogenously hypercholesterolemic (ExHC) rats. A deletion mutation in Smek2 leads to DIHC via impaired glycolysis in the livers of ExHC rats. The intrac...

Descripción completa

Detalles Bibliográficos
Autores principales: Tanaka, Yasutake, Kawano, Michio, Nakashima, Sawako, Yamaguchi, Chisato, Asahina, Makoto, Sakamoto, Mai, Shirouchi, Bungo, Tashiro, Kousuke, Imaizumi, Katsumi, Sato, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944932/
https://www.ncbi.nlm.nih.gov/pubmed/36810603
http://dx.doi.org/10.1038/s41598-022-26115-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944932/
https://www.ncbi.nlm.nih.gov/pubmed/36810603
http://dx.doi.org/10.1038/s41598-022-26115-z

Ejemplares similares