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LSM1-mediated Major Satellite RNA decay is required for nonequilibrium histone H3.3 incorporation into parental pronuclei

Epigenetic reprogramming of the parental genome is essential for zygotic genome activation and subsequent embryo development in mammals. Asymmetric incorporation of histone H3 variants into the parental genome has been observed previously, but the underlying mechanism remains elusive. In this study,...

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Detalles Bibliográficos
Autores principales: Zhu, Jiang, Chen, Kang, Sun, Yu H., Ye, Wen, Liu, Juntao, Zhang, Dandan, Su, Nan, Wu, Li, Kou, Xiaochen, Zhao, Yanhong, Wang, Hong, Gao, Shaorong, Kang, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944933/
https://www.ncbi.nlm.nih.gov/pubmed/36810573
http://dx.doi.org/10.1038/s41467-023-36584-z