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Clinically relevant increases in the international normalized ratio and model of end-stage liver disease score by therapeutic doses of direct oral anticoagulants in patients with cirrhosis

BACKGROUND: Patients with cirrhosis are increasingly using direct oral anticoagulants (DOACs) in therapeutic doses for the treatment of portal vein thrombosis or for concomitant atrial fibrillation. DOACs may affect routine diagnostic tests of coagulation including the international normalized ratio...

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Detalles Bibliográficos
Autores principales: Lisman, Ton, Bernal, William, Adelmeijer, Jelle, Kamphuisen, Pieter-Willem, Bos, Sarah, Porte, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944978/
https://www.ncbi.nlm.nih.gov/pubmed/36846648
http://dx.doi.org/10.1016/j.rpth.2023.100052