Spatially Resolved Top-Down Proteomics of Tissue Sections Based on a Microfluidic Nanodroplet Sample Preparation Platform

Conventional proteomic approaches measure the averaged signal from mixed cell populations or bulk tissues, leading to the dilution of signals arising from subpopulations of cells that might serve as important biomarkers. Recent developments in bottom-up proteomics have enabled spatial mapping of cel...

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Detalles Bibliográficos
Autores principales: Liao, Yen-Chen, Fulcher, James M., Degnan, David J., Williams, Sarah M., Bramer, Lisa M., Veličković, Dušan, Zemaitis, Kevin J., Veličković, Marija, Sontag, Ryan L., Moore, Ronald J., Paša-Tolić, Ljiljana, Zhu, Ying, Zhou, Mowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article Collection: Separation Technology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944986/
https://www.ncbi.nlm.nih.gov/pubmed/36603806
http://dx.doi.org/10.1016/j.mcpro.2022.100491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944986/
https://www.ncbi.nlm.nih.gov/pubmed/36603806
http://dx.doi.org/10.1016/j.mcpro.2022.100491

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