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Self-Assembled Oleic Acid-Modified Polyallylamines for Improved siRNA Transfection Efficiency and Lower Cytotoxicity

[Image: see text] Small interference RNA (siRNA) is a tool for gene modulation, which can silence any gene involved in genetic disorders. The potential of this therapeutic tool is hampered by RNA instability in the blood stream and difficulties to reach the cytosol. Polyamine-based nanoparticles pla...

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Detalles Bibliográficos
Autores principales: Salvador, Cristian, Andreozzi, Patrizia, Romero, Gabriela, Loinaz, Iraida, Dupin, Damien, Moya, Sergio E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945087/
https://www.ncbi.nlm.nih.gov/pubmed/36647574
http://dx.doi.org/10.1021/acsabm.2c00845