Recombinant Pichinde viral vector expressing tuberculosis antigens elicits strong T cell responses and protection in mice

INTRODUCTION: Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) remains a major global health threat. The only available vaccine Bacille Calmette-Guérin (BCG) does not prevent adult pulmonary TB. New effective TB vaccines should aim to stimulate robust T cell responses in the lung mucosa...

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Detalles Bibliográficos
Autores principales: Kirk, Natalie M., Huang, Qinfeng, Vrba, Sophia, Rahman, Mizanur, Block, Alisha M., Murphy, Hannah, White, Dylan W., Namugenyi, Sarah B., Ly, Hinh, Tischler, Anna D., Liang, Yuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945092/
https://www.ncbi.nlm.nih.gov/pubmed/36845108
http://dx.doi.org/10.3389/fimmu.2023.1127515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945092/
https://www.ncbi.nlm.nih.gov/pubmed/36845108
http://dx.doi.org/10.3389/fimmu.2023.1127515

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