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Read the clonotype: Next-generation sequencing-based lymphocyte clonality analysis and perspectives for application in pathology

Clonality assessment using the unique rearrangements of immunoglobulin (IG) and T-cell receptor (TR) genes in lymphocytes is a widely applied supplementary test for the diagnosis of B-cell and T-cell lymphoma. To enable a more sensitive detection and a more precise comparison of clones compared with...

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Detalles Bibliográficos
Autores principales: Groenen, Patricia J. T. A., van den Brand, Michiel, Kroeze, Leonie I., Amir, Avital L., Hebeda, Konnie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945094/
https://www.ncbi.nlm.nih.gov/pubmed/36845702
http://dx.doi.org/10.3389/fonc.2023.1107171