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Determination of the Binding Epitope of an Anti-Mouse CCR9 Monoclonal Antibody (C(9)Mab-24) Using the 1× Alanine and 2× Alanine-Substitution Method
C-C chemokine receptor 9 (CCR9) is a receptor for C-C-chemokine ligand 25 (CCL25). CCR9 is crucial in the chemotaxis of immune cells and inflammatory responses. Moreover, CCR9 is highly expressed in tumors, including several solid tumors and T-cell acute lymphoblastic leukemia. Several preclinical s...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945134/ https://www.ncbi.nlm.nih.gov/pubmed/36810516 http://dx.doi.org/10.3390/antib12010011 |