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Characterization of a Novel Thermostable DNA Lyase Used To Prepare DNA for Next-Generation Sequencing

[Image: see text] Recently, we constructed a hybrid thymine DNA glycosylase (hyTDG) by linking a 29-amino acid sequence from the human thymine DNA glycosylase with the catalytic domain of DNA mismatch glycosylase (MIG) from M. thermoautotrophicum, increasing the overall activity of the glycosylase....

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Detalles Bibliográficos
Autores principales: Baljinnyam, Tuvshintugs, Conrad, James W., Sowers, Mark L., Chang-Gu, Bruce, Herring, Jason L., Hackfeld, Linda C., Zhang, Kangling, Sowers, Lawrence C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945173/
https://www.ncbi.nlm.nih.gov/pubmed/36647573
http://dx.doi.org/10.1021/acs.chemrestox.2c00172