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Activating transcription factor 4 protects mice against sepsis-induced intestinal injury by regulating gut-resident macrophages differentiation

BACKGROUND: Gut-resident macrophages (gMacs) supplemented by monocytes-to-gMacs differentiation play a critical role in maintaining intestinal homeostasis. Activating transcription factor 4 (ATF4) is involved in immune cell differentiation. We therefore set out to investigate the role of ATF4-regula...

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Detalles Bibliográficos
Autores principales: Wen, Zhenliang, Xiong, Xi, Chen, Dechang, Shao, Lujing, Tang, Xiaomeng, Shen, Xuan, Zhang, Sheng, Huang, Sisi, Zhang, Lidi, Chen, Yizhu, Zhang, Yucai, Wang, Chunxia, Liu, Jiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945183/
https://www.ncbi.nlm.nih.gov/pubmed/36469355
http://dx.doi.org/10.1097/CM9.0000000000002543