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Engineering the kinetic stability of a β-trefoil protein by tuning its topological complexity
Kinetic stability, defined as the rate of protein unfolding, is central to determining the functional lifetime of proteins, both in nature and in wide-ranging medical and biotechnological applications. Further, high kinetic stability is generally correlated with high resistance against chemical and...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945329/ https://www.ncbi.nlm.nih.gov/pubmed/36845544 http://dx.doi.org/10.3389/fmolb.2023.1021733 |