Sex differences in the percentage of IRF5 positive B cells are associated with higher production of TNF-α in women in response to TLR9 in humans

BACKGROUND: The clinical course and outcome of many diseases differ between women and men, with women experiencing a higher prevalence and more severe pathogenesis of autoimmune diseases. The precise mechanisms underlying these sex differences still remain to be fully understood. IRF5 is a master tr...

Descripción completa

Detalles Bibliográficos
Autores principales: Beisel, Claudia, Jordan-Paiz, Ana, Köllmann, Sandra, Ahrenstorf, Annika Elise, Padoan, Benedetta, Barkhausen, Tanja, Addo, Marylyn M., Altfeld, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945365/
https://www.ncbi.nlm.nih.gov/pubmed/36814288
http://dx.doi.org/10.1186/s13293-023-00495-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945365/
https://www.ncbi.nlm.nih.gov/pubmed/36814288
http://dx.doi.org/10.1186/s13293-023-00495-x

Ejemplares similares