Cargando…

Sex differences in the percentage of IRF5 positive B cells are associated with higher production of TNF-α in women in response to TLR9 in humans

BACKGROUND: The clinical course and outcome of many diseases differ between women and men, with women experiencing a higher prevalence and more severe pathogenesis of autoimmune diseases. The precise mechanisms underlying these sex differences still remain to be fully understood. IRF5 is a master tr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Beisel, Claudia, Jordan-Paiz, Ana, Köllmann, Sandra, Ahrenstorf, Annika Elise, Padoan, Benedetta, Barkhausen, Tanja, Addo, Marylyn M., Altfeld, Marcus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945365/ https://www.ncbi.nlm.nih.gov/pubmed/36814288 http://dx.doi.org/10.1186/s13293-023-00495-x

Ejemplares similares

Frequency of IRF5+ dendritic cells is associated with the TLR7-induced inflammatory cytokine response in SARS-CoV-2 infection
por: Cords, Leon, et al.
Publicado: (2023)

Swine IRF3/IRF7 attenuates inflammatory responses through TLR4 signaling pathway
por: Chen, Pei-Ge, et al.
Publicado: (2017)

Higher Risk of HEV Transmission and Exposure among Blood Donors in Europe and Asia in Comparison to North America: A Meta-Analysis
por: Wolski, Annika, et al.
Publicado: (2023)

HCFC2 is needed for IRF1- and IRF2-dependent Tlr3 transcription and for survival during viral infections
por: Sun, Lei, et al.
Publicado: (2017)

DHEA-dependent and organ-specific regulation of TNF-α mRNA expression in a murine polymicrobial sepsis and trauma model
por: Barkhausen, Tanja, et al.
Publicado: (2009)

FcγR-TLR Cross-Talk Enhances TNF Production by Human Monocyte-Derived DCs via IRF5-Dependent Gene Transcription and Glycolytic Reprogramming
por: Hoepel, Willianne, et al.
Publicado: (2019)

Implications of post-translational modifications of IRF7 on pDC IFN-alpha response
por: Griesbeck, M, et al.
Publicado: (2012)

A phospho-tyrosine–based signaling module using SPOP, CSK, and LYN controls TLR-induced IRF activity
por: Tawaratsumida, Kazuki, et al.
Publicado: (2022)

The co-inhibitory receptor TIGIT regulates NK cell function and is upregulated in human intrahepatic CD56(bright) NK cells
por: Ziegler, Annerose E., et al.
Publicado: (2023)

Inborn errors underlying herpes simplex encephalitis: From TLR3 to IRF3
por: Zhang, Shen-Ying, et al.
Publicado: (2015)

MIP-1α Expression Induced by Co-Stimulation of Human Monocytic Cells with Palmitate and TNF-α Involves the TLR4-IRF3 Pathway and Is Amplified by Oxidative Stress
por: Sindhu, Sardar, et al.
Publicado: (2020)

Regulation of NK-Cell Function by HLA Class II
por: Niehrs, Annika, et al.
Publicado: (2020)

CD8+ T lymphocyte responses target functionally important regions of Protease and Integrase in HIV-1 infected subjects
por: Rodriguez, William R, et al.
Publicado: (2004)

TLR4 dependent heparan sulphate-induced pancreatic inflammatory response is IRF3-mediated
por: Akbarshahi, Hamid, et al.
Publicado: (2011)

People with HIV have higher percentages of circulating CCR5+ CD8+ T cells and lower percentages of CCR5+ regulatory T cells
por: van Eekeren, Louise E., et al.
Publicado: (2022)

CD36 neutralisation blunts TLR2-IRF7 but not IRF3 pathway in neonatal mouse brain and immature human microglia following innate immune challenge
por: Gadagkar, Shruti Gururaj, et al.
Publicado: (2023)

Dysregulated Tim-3 expression on natural killer cells is associated with increased Galectin-9 levels in HIV-1 infection
por: Jost, Stephanie, et al.
Publicado: (2013)

The TLR7/IRF-5 axis sensitizes memory CD4(+) T cells to Fas-mediated apoptosis during HIV-1 infection
por: Carmona-Pérez, Liseth, et al.
Publicado: (2023)

Increased percentages of calprotectin and TNF-Α double-positive monocytes in the acute phase of Kawasaki disease
por: Cimaz, Rolando, et al.
Publicado: (2011)

The Combination of IFN β and TNF Induces an Antiviral and Immunoregulatory Program via Non-Canonical Pathways Involving STAT2 and IRF9
por: Mariani, Mélissa K., et al.
Publicado: (2019)

TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9
por: Heinz, Leonhard X., et al.
Publicado: (2020)

TIRAP/Mal Positively Regulates TLR8-Mediated Signaling via IRF5 in Human Cells
por: Nilsen, Kaja Elisabeth, et al.
Publicado: (2022)

TLR-4, TLR-5 and IRF4 are diagnostic markers of knee osteoarthritis in the middle-aged and elderly patients and related to disease activity and inflammatory factors
por: Han, Wenchao, et al.
Publicado: (2020)

Stearic Acid and TNF-α Co-Operatively Potentiate MIP-1α Production in Monocytic Cells via MyD88 Independent TLR4/TBK/IRF3 Signaling Pathway
por: Kochumon, Shihab, et al.
Publicado: (2020)

Higher Percentage of Patients Return to Work than Sport Following Tibial Tubercle Anteromedialization
por: Bloom, David, et al.
Publicado: (2020)

Higher percentage of horse serum in culture media blocks attachment of PC12 cells
por: Meth, Jennifer L, et al.
Publicado: (2019)

Is there higher percentage of undetected osteopenia and osteoporosis among patients with ulcerative colitis in Saudi Arabia?
por: Olic Akrapovic, Ivna, et al.
Publicado: (2021)

Higher Responsiveness for Women, High Transaminase Levels, and Fat Percentage to Pemafibrate Treatment for NAFLD
por: Iwadare, Takanobu, et al.
Publicado: (2022)

Clinical Presentation and Disease Course of 37 Consecutive Cases of Progressive Multifocal Leukoencephalopathy (PML) at a German Tertiary-Care Hospital: A Retrospective Observational Study
por: Graf, Lisa M., et al.
Publicado: (2021)

IRF7 Regulates TLR2-Mediated Activation of Splenic CD11c(hi) Dendritic Cells
por: Owens, Benjamin M. J., et al.
Publicado: (2012)

HSV-2 Increases TLR4-Dependent Phosphorylated IRFs and IFN-β Induction in Cervical Epithelial Cells
por: Liu, Hongya, et al.
Publicado: (2014)

Limited Durability of Viral Control following Treated Acute HIV Infection
por: Kaufmann, Daniel E, et al.
Publicado: (2004)

TRIM14 expression is regulated by IRF‐1 and IRF‐2
por: Cui, Jingang, et al.
Publicado: (2019)

A simple, sensitive, and low‐cost FACS assay for detecting antibodies against the native SARS‐CoV‐2 spike protein
por: Hambach, Julia, et al.
Publicado: (2021)

LPS-TLR4 Signaling to IRF-3/7 and NF-κB Involves the Toll Adapters TRAM and TRIF
por: Fitzgerald, Katherine A., et al.
Publicado: (2003)

The TLR3/IRF1/Type III IFN Axis Facilitates Antiviral Responses against Enterovirus Infections in the Intestine
por: Su, Rui, et al.
Publicado: (2020)

Transcriptome Analysis of Microglia Reveals That the TLR2/IRF7 Signaling Axis Mediates Neuroinflammation After Subarachnoid Hemorrhage
por: Xu, Shenbin, et al.
Publicado: (2021)

A p53-TLR3 axis ameliorates pulmonary hypertension by inducing BMPR2 via IRF3
por: Bhagwani, Aneel R., et al.
Publicado: (2023)

TLR8 regulation of LILRA3 in monocytes is abrogated in human immunodeficiency virus infection and correlates to CD4 counts and virus loads
por: Low, Hui Zhi, et al.
Publicado: (2016)

Parts and Percentage
Publicado: (1891)

Cannot write session to /tmp/vufind_sessions/sess_levn94jebsed9c0e42b4fha7g6