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Up-regulation of HCN2 channels in a thalamocortical circuit mediates allodynia in mice

Chronic pain is a significant problem that afflicts individuals and society, and for which the current clinical treatment is inadequate. In addition, the neural circuit and molecular mechanisms subserving chronic pain remain largely uncharacterized. Herein we identified enhanced activity of a glutam...

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Detalles Bibliográficos
Autores principales: Yu, Jun-Ma, Hu, Rui, Mao, Yu, Tai, Yingju, Qun, Sen, Zhang, Zhi, Chen, Danyang, Jin, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945406/
https://www.ncbi.nlm.nih.gov/pubmed/36846300
http://dx.doi.org/10.1093/nsr/nwac275