Cargando…
Up-regulation of HCN2 channels in a thalamocortical circuit mediates allodynia in mice
Chronic pain is a significant problem that afflicts individuals and society, and for which the current clinical treatment is inadequate. In addition, the neural circuit and molecular mechanisms subserving chronic pain remain largely uncharacterized. Herein we identified enhanced activity of a glutam...
Autores principales: | Yu, Jun-Ma, Hu, Rui, Mao, Yu, Tai, Yingju, Qun, Sen, Zhang, Zhi, Chen, Danyang, Jin, Yan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945406/ https://www.ncbi.nlm.nih.gov/pubmed/36846300 http://dx.doi.org/10.1093/nsr/nwac275 |
Ejemplares similares
-
Thalamocortical circuits drive remifentanil-induced postoperative hyperalgesia
por: Jin, Yan, et al.
Publicado: (2022) -
Targeted Deletion of Kcne2 Impairs HCN Channel Function in Mouse Thalamocortical Circuits
por: Ying, Shui-Wang, et al.
Publicado: (2012) -
Thalamocortical Circuit Controls Neuropathic Pain via Up-regulation of HCN2 in the Ventral Posterolateral Thalamus
por: Yan, Yi, et al.
Publicado: (2022) -
Modulation of thalamocortical oscillations by TRIP8b, an auxiliary subunit for HCN channels
por: Zobeiri, Mehrnoush, et al.
Publicado: (2017) -
The Hyperpolarization-Activated HCN4 Channel is Important for Proper Maintenance of Oscillatory Activity in the Thalamocortical System
por: Zobeiri, Mehrnoush, et al.
Publicado: (2019)