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Z-RNA biology: a central role in the innate immune response?

Z-RNA is a higher-energy, left-handed conformation of RNA, whose function has remained elusive. A growing body of work alludes to regulatory roles for Z-RNA in the immune response. Here, we review how Z-RNA features present in cellular RNAs—especially containing retroelements—could be recognized by...

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Detalles Bibliográficos
Autores principales: Nichols, Parker J., Krall, Jeffrey B., Henen, Morkos A., Vögeli, Beat, Vicens, Quentin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945438/
https://www.ncbi.nlm.nih.gov/pubmed/36596670
http://dx.doi.org/10.1261/rna.079429.122