In vivo PIWI slicing in mouse testes deviates from rules established in vitro

Argonautes are small RNA-binding proteins, with some having small RNA-guided endonuclease (slicer) activity that cleaves target nucleic acids. One cardinal rule that is structurally defined is the inability of slicers to cleave target RNAs when nucleotide mismatches exist between the paired small RN...

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Detalles Bibliográficos
Autores principales: Dowling, Mark, Homolka, David, Raad, Nicole, Gos, Pascal, Pandey, Radha Raman, Pillai, Ramesh S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945443/
https://www.ncbi.nlm.nih.gov/pubmed/36617658
http://dx.doi.org/10.1261/rna.079349.122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945443/
https://www.ncbi.nlm.nih.gov/pubmed/36617658
http://dx.doi.org/10.1261/rna.079349.122

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