DNMT1 inhibition by pUG-fold quadruplex RNA

Aberrant DNA methylation is one of the earliest hallmarks of cancer. DNMT1 is responsible for methylating newly replicated DNA, but the precise regulation of DNMT1 to ensure faithful DNA methylation remains poorly understood. A link between RNA and chromatin-associated proteins has recently emerged,...

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Detalles Bibliográficos
Autores principales: Jansson-Fritzberg, Linnea I., Sousa, Camila I., Smallegan, Michael J., Song, Jessica J., Gooding, Anne R., Kasinath, Vignesh, Rinn, John L., Cech, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945446/
https://www.ncbi.nlm.nih.gov/pubmed/36574982
http://dx.doi.org/10.1261/rna.079479.122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945446/
https://www.ncbi.nlm.nih.gov/pubmed/36574982
http://dx.doi.org/10.1261/rna.079479.122

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