Neural mechanism underlies CYLD modulation of morphology and synaptic function of medium spiny neurons in dorsolateral striatum

Although the deubiquitinase cylindromatosis (CYLD), an abundant protein in the postsynaptic density fraction, plays a crucial role in mediating the synaptic activity of the striatum, the precise molecular mechanism remains largely unclear. Here, using a Cyld-knockout mouse model, we demonstrate that...

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Detalles Bibliográficos
Autores principales: Tan, Shu-yi, Jiang, Jin-xiang, Huang, Hui-xian, Mo, Xiu-ping, Feng, Jing-ru, Chen, Yu, Yang, Li, Long, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945542/
https://www.ncbi.nlm.nih.gov/pubmed/36846565
http://dx.doi.org/10.3389/fnmol.2023.1107355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945542/
https://www.ncbi.nlm.nih.gov/pubmed/36846565
http://dx.doi.org/10.3389/fnmol.2023.1107355

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