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Neural mechanism underlies CYLD modulation of morphology and synaptic function of medium spiny neurons in dorsolateral striatum
Although the deubiquitinase cylindromatosis (CYLD), an abundant protein in the postsynaptic density fraction, plays a crucial role in mediating the synaptic activity of the striatum, the precise molecular mechanism remains largely unclear. Here, using a Cyld-knockout mouse model, we demonstrate that...
Autores principales: | Tan, Shu-yi, Jiang, Jin-xiang, Huang, Hui-xian, Mo, Xiu-ping, Feng, Jing-ru, Chen, Yu, Yang, Li, Long, Cheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945542/ https://www.ncbi.nlm.nih.gov/pubmed/36846565 http://dx.doi.org/10.3389/fnmol.2023.1107355 |
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