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Investigating associations between blood metabolites, later life brain imaging measures, and genetic risk for Alzheimer’s disease

BACKGROUND: Identifying blood-based signatures of brain health and preclinical pathology may offer insights into early disease mechanisms and highlight avenues for intervention. Here, we systematically profiled associations between blood metabolites and whole-brain volume, hippocampal volume, and am...

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Detalles Bibliográficos
Autores principales: Green, Rebecca E., Lord, Jodie, Scelsi, Marzia A., Xu, Jin, Wong, Andrew, Naomi-James, Sarah, Handy, Alex, Gilchrist, Lachlan, Williams, Dylan M., Parker, Thomas D., Lane, Christopher A., Malone, Ian B., Cash, David M., Sudre, Carole H., Coath, William, Thomas, David L., Keuss, Sarah, Dobson, Richard, Legido-Quigley, Cristina, Fox, Nick C., Schott, Jonathan M., Richards, Marcus, Proitsi, Petroula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945600/
https://www.ncbi.nlm.nih.gov/pubmed/36814324
http://dx.doi.org/10.1186/s13195-023-01184-y