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PINK1 protects against dendritic cell dysfunction during sepsis through the regulation of mitochondrial quality control
BACKGROUND: Dendritic cell (DC) dysfunction plays a central role in sepsis-induced immunosuppression. Recent research has indicated that collective mitochondrial fragmentation contributes to the dysfunction of immune cells observed during sepsis. PTEN-induced putative kinase 1 (PINK1) has been chara...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945621/ https://www.ncbi.nlm.nih.gov/pubmed/36809929 http://dx.doi.org/10.1186/s10020-023-00618-5 |