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PINK1 protects against dendritic cell dysfunction during sepsis through the regulation of mitochondrial quality control

BACKGROUND: Dendritic cell (DC) dysfunction plays a central role in sepsis-induced immunosuppression. Recent research has indicated that collective mitochondrial fragmentation contributes to the dysfunction of immune cells observed during sepsis. PTEN-induced putative kinase 1 (PINK1) has been chara...

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Detalles Bibliográficos
Autores principales:	Wu, You, Chen, Longwang, Qiu, Zhimin, Zhang, Xijing, Zhao, Guangju, Lu, Zhongqiu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945621/ https://www.ncbi.nlm.nih.gov/pubmed/36809929 http://dx.doi.org/10.1186/s10020-023-00618-5

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