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Enhanced liquidity of p62 droplets mediated by Smurf1 links Nrf2 activation and autophagy
BACKGROUND: Macro-autophagy/Autophagy is an evolutionarily well-conserved recycling process to maintain the balance through precise spatiotemporal regulation. However, the regulatory mechanisms of biomolecular condensates by the key adaptor protein p62 via liquid-liquid phase separation (LLPS) remai...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945626/ https://www.ncbi.nlm.nih.gov/pubmed/36810259 http://dx.doi.org/10.1186/s13578-023-00978-9 |