Cargando…

Enhanced liquidity of p62 droplets mediated by Smurf1 links Nrf2 activation and autophagy

BACKGROUND: Macro-autophagy/Autophagy is an evolutionarily well-conserved recycling process to maintain the balance through precise spatiotemporal regulation. However, the regulatory mechanisms of biomolecular condensates by the key adaptor protein p62 via liquid-liquid phase separation (LLPS) remai...

Descripción completa

Detalles Bibliográficos
Autores principales: Xia, Qin, Li, Yang, Xu, Wanting, Wu, Chengwei, Zheng, Hanfei, Liu, Liqun, Dong, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945626/
https://www.ncbi.nlm.nih.gov/pubmed/36810259
http://dx.doi.org/10.1186/s13578-023-00978-9