Hypoxia-induced downregulation of microRNA-186-5p in endothelial cells promotes non-small cell lung cancer angiogenesis by upregulating protein kinase C alpha

The tumor microenvironment stimulates the angiogenic activity of endothelial cells (ECs) to facilitate tumor vascularization, growth, and metastasis. The involvement of microRNA-186-5p (miR-186) in regulating the aberrant activity of tumor-associated ECs has so far not been clarified. In the present...

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Detalles Bibliográficos
Autores principales: Becker, Vivien, Yuan, Xu, Boewe, Anne S., Ampofo, Emmanuel, Ebert, Elke, Hohneck, Johannes, Bohle, Rainer M., Meese, Eckart, Zhao, Yingjun, Menger, Michael D., Laschke, Matthias W., Gu, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945639/
https://www.ncbi.nlm.nih.gov/pubmed/36845338
http://dx.doi.org/10.1016/j.omtn.2023.01.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945639/
https://www.ncbi.nlm.nih.gov/pubmed/36845338
http://dx.doi.org/10.1016/j.omtn.2023.01.015

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