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Hypoxia-induced downregulation of microRNA-186-5p in endothelial cells promotes non-small cell lung cancer angiogenesis by upregulating protein kinase C alpha
The tumor microenvironment stimulates the angiogenic activity of endothelial cells (ECs) to facilitate tumor vascularization, growth, and metastasis. The involvement of microRNA-186-5p (miR-186) in regulating the aberrant activity of tumor-associated ECs has so far not been clarified. In the present...
Autores principales: | Becker, Vivien, Yuan, Xu, Boewe, Anne S., Ampofo, Emmanuel, Ebert, Elke, Hohneck, Johannes, Bohle, Rainer M., Meese, Eckart, Zhao, Yingjun, Menger, Michael D., Laschke, Matthias W., Gu, Yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945639/ https://www.ncbi.nlm.nih.gov/pubmed/36845338 http://dx.doi.org/10.1016/j.omtn.2023.01.015 |
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