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Fat infiltration in the thigh muscles is associated with symptomatic spinal stenosis and reduced physical functioning in adults with achondroplasia

BACKGROUND: Symptomatic spinal stenosis is a prevalent complication in adults with achondroplasia. Increased muscle fat infiltration (MFI) and reduced thigh muscle volumes have also been reported, but the pathophysiology is poorly understood. We explored whether the increased MFI and reduced thigh m...

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Detalles Bibliográficos
Autores principales: Fredwall, Svein O., Linge, Jennifer, de Vries, Olga, Leinhard, Olof Dahlqvist, Eggesbø, Heidi Beate, Weedon-Fekjær, Harald, Petersson, Mikael, Widholm, Per, Månum, Grethe, Savarirayan, Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945720/
https://www.ncbi.nlm.nih.gov/pubmed/36814258
http://dx.doi.org/10.1186/s13023-023-02641-5