Nitazoxanide inhibits acetylated KLF5-induced bone metastasis by modulating KLF5 function in prostate cancer

BACKGROUND: Castration-resistant prostate cancer often metastasizes to the bone, and such bone metastases eventually become resistant to available therapies, leading to the death of patients. Enriched in the bone, TGF-β plays a pivotal role in bone metastasis development. However, directly targeting...

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Detalles Bibliográficos
Autores principales: Huang, Qingqing, Liu, Mingcheng, Zhang, Duo, Lin, Bing-Biao, Fu, Xing, Zhang, Zhiqian, Zhang, Baotong, Dong, Jin-Tang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945734/
https://www.ncbi.nlm.nih.gov/pubmed/36810084
http://dx.doi.org/10.1186/s12916-023-02763-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945734/
https://www.ncbi.nlm.nih.gov/pubmed/36810084
http://dx.doi.org/10.1186/s12916-023-02763-4

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