Self-attention enabled deep learning of dihydrouridine (D) modification on mRNAs unveiled a distinct sequence signature from tRNAs

Dihydrouridine (D) is a modified pyrimidine nucleotide universally found in viral, prokaryotic, and eukaryotic species. It serves as a metabolic modulator for various pathological conditions, and its elevated levels in tumors are associated with a series of cancers. Precise identification of D sites...

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Detalles Bibliográficos
Autores principales: Wang, Yue, Wang, Xuan, Cui, Xiaodong, Meng, Jia, Rong, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945750/
https://www.ncbi.nlm.nih.gov/pubmed/36845339
http://dx.doi.org/10.1016/j.omtn.2023.01.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945750/
https://www.ncbi.nlm.nih.gov/pubmed/36845339
http://dx.doi.org/10.1016/j.omtn.2023.01.014

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